Expresión de búsqueda:
MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES
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DeCS
Descriptor
Inglés
:
Mannose-Binding Protein-Associated Serine Proteases
Descriptor
Español
:
Serina Proteasas Asociadas a la Proteína de Unión a la Manosa
Descriptor
Portugués
:
Serina Proteases Associadas a Proteína de Ligação a Manose
Categoría:
D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
Definición
Inglés
:
Serum
serine proteases
which participate in
COMPLEMENT ACTIVATION
. They are activated when complexed with the
MANNOSE-BINDING LECTIN
, therefore also known as
Mannose-binding protein-Associated Serine Proteases
(MASPs). They cleave
COMPLEMENT C4
and
COMPLEMENT C2
to form C4b2a, the CLASSICAL PATHWAY
C3 CONVERTASE.
Nota de Indización
Inglés
:
see SCR for organism-specific terms
Acción Farmacológica:
Immunologic Factors
Nota Histórica
Inglés
:
2006 (1994)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
50582
Identificador Único:
D050606
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS